2型糖尿病合并高血压发生脑卒中的临床特点及相关危险因素分析

郎琪+杨礼环

[摘要] 目的 探討2型糖尿病合并高血压发生脑卒中的临床特点及相关危险因素。方法 方便选取重庆市渝北区人民医院2010年1月—2015年12月收治的2型糖尿病合并高血压患者540例，按是否发生脑卒中分为2型糖尿病合并高血压合并脑卒中组和2型糖尿病合并高血压组。比较两组间年龄、性别、吸烟史，饮酒史，心脏病史、肥胖和各项生化指标的差异，分析高血压分级、糖尿病病程对发生脑卒中的影响，采用Logistic 回归分析型糖尿病合并高血压发生脑卒中的相关危险因素。结果 型糖尿病合并高血压合并脑卒中组与单纯2型糖尿病合并高血压组比较，发生脑卒中组年龄（64.00±12.30）岁，较未发生脑卒中组年龄（59.18±14.69）岁大（t=-2.081， P=0.039<0.05），血糖异常率及血红蛋白异常率高（P<0.01），糖尿病病程长（P<0.001），处于高血压2、3级人数多（P<0.01）；多元Logistic回归分析结果显示年龄（OR=1.089，P=0.007）、糖尿病病程（OR=1.631，P=0.001）、血糖水平（OR=1.951，P=0.003），颈动脉斑块（OR=5.976，P=0.036）为2型糖尿病合并高血压发生脑卒中的危险因素。结论 2型糖尿病合并高血压发生脑卒中与患者血压、血糖、血脂、糖尿病病程、颈动脉斑块形成有关。

[关键词] 糖尿病；高血压；脑卒中；危险因素

[中图分类号] R587 [文献标识码] A [文章编号] 1674-0742（2017）09（c）-0004-04

Analysis of Clinical Features and Related Risk Factors of Stroke Patients with Type 2 Diabetes and Hypertension

LANG Qi， YANG Li-huan

Department of Neurology， Yubei District Peoples Hospital， Chongqing， 401120 China

[Abstract] Objective To study the clinical features and related risk factors of stroke patients with type II diabetes and hypertension. Methods 540 cases of patients with type 2 diabetes and hypertension in our hospital from January 2010 to December 2015 were convenient selected and divided into two groups according to whether the patients were with stroke， and the age， gender， smoking history， alcohol history， cardiac disease history， obesity and various biochemical indexes of the two groups were compared， and the effect of hypertension classification and diabetes course on the stroke was analyzed and the related risk factors of stroke patients with type 2 diabetes and hypertension were analyzed by the Logistic regression. Results The age in the type 2 diabetes and hypertension and stroke group was older than that of simple type 2 diabetes and hypertension group， [（64.00±12.30）years old vs（59.18±14.69）years old]， （t=-2.081， P=0.039<0.05）， and the abnormality rates of blood glucose and hemoglobin were higher（P<0.01）， and the diabetes course was longer（P<0.001）， and the cases with second-level and third-level hypertension were most（P<0.01）； and the multi-Logistic regression analysis results showed that the （OR=1.089， P=0.007）， diabetes course（OR=1.631， P=0.001）， blood glucose level （OR=1.951，P=0.003） and carotid plaque （OR=5.976， P=0.036） were the risk factors of stroke patients with type 2 diabetes and hypertension. Conclusion The patients with type 2 diabetes and hypertension are related to the blood hypertension， blood glucose， blood liquid， diabetes course and carotid plaque formation.endprint